K-State research underscores complexity of treating bovine respiratory disease

University field trials highlight the need for case-specific decisions in managing cattle health and economics


By Chevy-Lynn Vaske
, K-State Extension news service

MANHATTAN, Kan. – Rising input costs and growing demands to improve cattle health are pushing producers to look closely at how they manage bovine respiratory disease (BRD), one of the beef industry’s most persistent health challenges.

Researchers at Kansas State University’s College of Veterinary Medicine recently shared findings from three field trials that tested treatment strategies in real-world feedlot settings.

“We’re always looking for ways to improve animal health,” said David Renter, a professor of epidemiology and director of K-State’s Center for Outcomes Research and Epidemiology (CORE). “Especially right now, it’s critical to understand how to help more animals make it across the finish line – through that high-risk sickness period and into providing safe, wholesome beef.”

Renter emphasized the purpose of the studies was not to make broad recommendations but to generate high-quality data that veterinarians and producers can use when making case-specific treatment decisions.

“That really is the mission of our center – to provide good information to the people who need it most,” he said.

The three trials were conducted over several years in collaboration with veterinarians and producers. Calves at varying levels of disease risk were enrolled, and those diagnosed with BRD were randomly assigned to different antibiotic treatments. Researchers tracked such outcomes as mortality, retreatment and chronic illness.

The first trial, which focused on high-risk calves that received metaphylaxis upon arrival, found no significant difference between two treatment options. The second trial, conducted in a similar population but with an added treatment group, found that one option significantly reduced mortality.

“These three studies reflect something we have seen time and time again in BRD research:, there is no single best treatment,” Renter said. “Outcomes are often inconsistent because the cattle we bring into backgrounding and feedlot operations are so different from one another. That’s why treatment choices really have to be made in consultation with a veterinarian who understands your specific cattle and operation.”

The team also evaluated the economic impact of disease intervention.

“The economics matter more now than they ever did a year ago,” Renter said. “Cattle are worth a lot more. So reducing death loss can have a much bigger payoff. But those returns are going to depend on the level of disease you’re seeing and what the intervention costs.”

To assist producers, a spreadsheet calculator is available at AgManager.info to help determine whether a treatment strategy may pay off in a specific operation.

For more information, listen to the full discussion on Agriculture Today.

Hot this week

🎙️ Tom Ford, Rozet Raven Studio Campfire Chat

Tom Ford with Rozet Raven Studio stops in to...

Marysville Weighs Historic Departure from NCKL for Big East League

Marysville, KS, is considering a league shift from the North Central Kansas League (NCKL) to the Big East League due to enrollment disparities. With projections indicating that Marysville will be the smallest member in the NCKL, school officials believe that joining the Big East could enhance competitiveness and better match the school's size and resources.

🎙️ K-State Agriculture Today: 2169 – Cattle Market Factors and Impacts…Encountering Snakes

Cattle Market, Beef Production and Weather Impacts Knowing How to...

🎙️ K-State Agriculture Today: 2168 – Getting More Grain Market Data…Cattle Turnout Illnesses

Grain Prices and Exports Cattle Health Considerations for Pasture and...

Beloit and Smith Center Dominate at Phillipsburg Invitational 2026

On April 24, 2026, Phillipsburg High School hosted the Phillipsburg Invitational, showcasing top performances from local athletes. Beloit girls secured victory with 214 points, while Smith Center boys led with 134 points. Notable individual wins included Dakota Gray, Gavin Hickert, and other standout athletes from various schools.

Latest Headlines

🎙️ Brady True Blood Pressure TWD

Brady True talks with Lydia about Blood Pressure on...

🎙️ K-State Agriculture Today: 2171 – FSA Drought Program…Stunted or Low Performing Alfalfa

FSA Disaster Program and Northwest Offices Alfalfa Issues and Concerns Cattle...

No. 16 Nebraska Walks Off Cats Tuesday, 7-6

K-State held a 6-4 lead but lost 7-6 to No. 16 Nebraska in a walk-off victory. Nebraska's Jeter Worthley tied the game with an RBI triple, and Rhett Stokes delivered the winning hit. K-State gave up three early runs and struggled with key plays, ultimately falling short in their comeback effort.

No. 11 Kansas Extends Win Streak with 14-1 Run-Rule Victory at Wichita State

No. 11 Kansas Baseball achieved a 14-1 victory over Wichita State, marking their seventh consecutive win and 18 of 19 overall. The Jayhawks improved to 34-11, finishing 9-0 against regional opponents. Jordan Bach led with four RBIs as six players recorded multi-hit games. Kansas will face Arizona next.
- Advertisement -

Related Articles

Popular Categories

- Advertisement -