USDA-NIFA Grant Supports Efforts To Control Viral Diseases in Swine


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Courtesy of Kansas State University

MANHATTAN — A $475,000 grant will help a Kansas State University research laboratory determine methods to control two of the most important viral agents in pigs: porcine reproductive and respiratory syndrome virus and swine influenza A virus.

Yunjeong Kim, associate professor of diagnostic medicine and pathobiology in the College of Veterinary Medicine, is the principal investigator on the grant from the U.S. Department of Agriculture National Institute of Food and Agriculture. The project will focus on gaining a better understanding of protein disulfide isomerases enzymes as a potential target for developing intervention strategies against porcine reproductive and respiratory syndrome virus, or PRRSV, and swine influenza A virus, or SIAV.

“SIAV and PPRSV are two of the most important viral agents in pigs,” Kim said. “Controlling these viruses is crucial for the swine production industry and sustained food supply, as well as for mitigating risks of potential pandemic influenza outbreaks in humans.”

Kim said there is an unmet need for safe and effective prevention and control measures.

“Identification and manipulation of host factors critical for virus infection may provide the foundation for devising novel intervention strategies,” Kim said. “Our group recently found that protein disulfide isomerases, which are involved in proper protein folding, play a key role for the replication of SIAV and PRRSV in cells by conducting experiments, including gene knockdown or CRISPR-based gene-editing technologies in cells.”

The grant is titled “Investigation of genetic factors for swine influenza A virus and porcine reproductive and respiratory syndrome virus.”

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Derek Nester
Derek Nesterhttps://sunflowerstateradio.com
Derek Nester was born and raised in Blue Rapids and graduated from Valley Heights High School in 2000. He attended Cowley College in Arkansas City and Johnson County Community College in Overland Park studying Journalism & Media Communications. In 2002 Derek joined Taylor Communications, Inc. in Salina, Kansas working in digital media for 550 AM KFRM and 100.9 FM KCLY. Following that stop, he joined Dierking Communications, Inc. stations KNDY AM & FM as a board operator and fill-in sports play-by-play announcer. Starting in 2005 Derek joined the Kansas City Chiefs Radio Network as a Studio Coordinator at 101 The Fox in Kansas City, a role he would serve for 15 years culminating in the Super Bowl LIV Championship game broadcast. In 2021 he moved to Audacy, formerly known as Entercom Communications, Inc. and 106.5 The Wolf and 610 Sports Radio, the new flagship stations of the Kansas City Chiefs Radio Network, the largest radio network in the NFL. Through all of this, Derek continues to serve as the Digital Media Director for Sunflower State Radio, the digital and social media operations of Dierking Communications, Inc. and the 6 radio stations it owns and operates across Kansas.

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